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Fentanyl is a very powerful opioid, about 100 times more toxic than morphine. It has been used for many years in medicine to relieve pain. When fentanyl is prescribed it usually comes in the form of a patch, and is generally safe. Powdered fentanyl is now being imported and sold illegally, which has resulted in a rise in overdoses. This illegal fentanyl is sometimes referred to as “bootleg fentanyl.” One step to purchase Carfentanil Crystal Online

There are many different forms (also called analogues) of fentanyl, with various different strengths. Carfentanil is one form of fentanyl that is about 100 times stronger than fentanyl (or 10,000 times stronger than morphine!) and was invented for use on large animals, like elephants. Carfentanil has become a problem in Manitoba, leading to fatal and non-fatal overdose.

Fentanyl and carfentanil are being added to other drugs, such as cocaine, fake (counterfeit) pills, crystal methamphetamine, MDMA, LSD, and ketamine, making the illegal drug market more dangerous.

Fentanyl (also spelled fentanil) is an opioid used as a pain medication and together with other medications for anesthesia. Fentanyl is also made illegally and used as a recreational drug, often mixed with heroin or cocaine. It has a rapid onset and effects generally last less than an hour or two. Medically, fentanyl is used by injection, as a patch on the skin, as a nasal spray, or in the mouth. Buy Fentanyl Patch Online

Common side effects include vomiting, constipation, sedation, confusion, hallucinations, and injuries related to poor coordination. Serious side effects may include decreased breathing (respiratory depression), serotonin syndrome, low blood pressure, addiction, or coma. In 2016, more than 20,000 deaths occurred in the United States due to overdoses of fentanyl and fentanyl analogues, half of all reported opioid – related deaths. Fentanyl works primarily by activating μ – opioid receptors. It is around 100 times stronger than morphine, and some analogues such as carfentanil are around 10,000 times stronger.

Medical uses

Intravenous fentanyl is often used for anaesthesia and analgesia. During anaesthesia it is often used along with a hypnotic agent like propofol. It is also administered in combination with a benzodiazepine, such as midazolam, to produce sedation for procedures such as endoscopy, cardiac catheterization, and oral surgery, or in emergency rooms. It is also used in the management of chronic pain including cancer pain.

Fentanyl is sometimes given intrathecally as part of spinal anaesthesia or epidurally for epidural anaesthesia and analgesia. Because of fentanyl’s high lipid solubility, its effects are more localized than morphine, and some clinicians prefer to use morphine to get a wider spread of analgesia.

Patches

A fentanyl transdermal patch with a release rate of 12 micrograms / hour, on a person’s arm.
Fentanyl transdermal patches are used in chronic pain management. The patches work by slowly releasing fentanyl through the skin into the bloodstream over 48 to 72 hours, allowing for long – lasting pain management. Dosage is based on the size of the patch, since, in general, the transdermal absorption rate is constant at a constant skin temperature. Rate of absorption is dependent on a number of factors. Body temperature, skin type, amount of body fat, and placement of the patch can have major effects. The different delivery systems used by different makers will also affect individual rates of absorption. Under normal circumstances, the patch will reach its full effect within 12 to 24 hours; thus, fentanyl patches are often prescribed with a fast – acting opioid (such as morphine or oxycodone) to handle breakthrough pain.

Storage and disposal

The fentanyl patch is one of a small number of medications that may be especially harmful, and in some cases fatal, with just one dose, if used by someone other than the person for whom the medication was prescribed.  Unused fentanyl patches should be kept in a secure location that is out of children’s sight and reach, such as a locked cabinet.

When patches cannot be disposed of through a medication take – back program, flushing is recommended for fentanyl patches because it is the fastest and surest way to remove them from the home so they cannot harm children, pets and others who were not intended to use them.